This study is to acquire the relationship between organic substances in water and prevalence of Kashin Beck disease (KBD). We sampled in three endemic areas and their corresponding neighboring non endemic areas, determined the contents of organic substances and examined the children. The results showed that:①humus type B exited only in endemic areas; ②the content of humus type B is proportional to the state of the illness. KBD may be related to the humus type B in drinking water.
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