ANALYSIS ON GENETIC POLYMORPHISM OF 6 STR LOCI ON CHROMOSOME 12 IN CHINESE HAN POPULATION

摘要

Shorttandemrepeats(STRs)arearichsource ofhighlypolymorphicmarkersinthehumange nome,arerelativelysmallinsize,andcanbestud iedwiththerelativeexpediently.ThustheSTR polymorphismsarehighlyusefultoolsforlinkagea nalysisofdisease relatedgenesandconstructionthe geneticmap.ManyofSTRsiteshavebeenusedtogeneratea genome widelinkagemapsuitableformappingdis easegeneloci.Forexample,about70genesrelated todiseaseshavebeenlocatedon12chromosome now[1].BecauseSTRPspresenthighheterozygosi tiesandgeneticdiversities,thegeneticpa...