EXPRESSION OF MATRIX METALLOPROTEINASE-2 AND VASCULAR ENDOTHELIAL GROWTH FACTOR IN HUMAN GLIOMA AND THEIR RELATION TO THE INVASION OF THE TUMOR

摘要

Neovascularizationcanbeobservedinthe courseoftumorformationandmalignantinvasion,whichwillpromotethemalignantinvasionofthe tumor[1].Vascularendothelialgrowthfactor(VEGF)andmatrixmetalloproteinases(MMPs)are theimportantadjustiveproteinsintheinvasionand neovascularizationoftumor[2,3].Thepresentstudy wasdesignedtoexploretheexpressionofVEGFand MMPsinhumangliomaandtoinvestigatetheirre lationtothepathologicalgradeandinvasionofthe tumorbyimmunohistochemicaltechnique.MATERIALSANDMETHODS1Materials Specimensusedinthis...