康肾散治疗慢性肾小球肾炎尿蛋白的临床观察

摘要

Objective:To quantify the scoring criteria for scoring method, observation of Kangshen powder in treating chronic glomerulonephritis clinical effect. Methods: 60 cases of patients with chronic glomerulonephritis according to stochastic grouping method is divided into the treatment group (kidney Kang San group) in 30 cases and the control group (Benner Pury) in 30 cases. After 8 weeks of treatment were observed in 24 hour urine protein, TCM syndrome efficacy, quality of life and the total effect index changes. Results: among two groups of the total efficiency of a very significant difference (P<0.01), the treatment group was better than control group; among the two groups in fall 24 hour urine protein function has significant difference (P<0.05), the treatment group than in control group; the clinical effect between the two groups and the clinical syndrome symptoms improved significantly differences (P<0.01), the treatment group was better than control group. Conclusion: Kangshen powder not only can significantly improve chronic glomerulonephritis patients tired, eat less respectively, China face, low back pain, edema and other clinical symptoms, but also can reduce 24 hour urinary protein, found no adverse reaction.%目的：以量化评分标准为评分手段，观察康肾散治疗慢性肾小球肾炎的临床效果。方法：将60例慢性肾小球肾炎患者按照随机分组方法分为治疗组（康肾散组）30例和对照组（贝那普利组）30例。经8周治疗后观察24小时尿蛋白定量、中医症候疗效、生活质量及总疗效等指标的变化。结果：两组间总有效率有显著差异（P＜0.01），治疗组显著优于对照组；两组间降24小时尿蛋白的作用有显著差异（P＜0.05），治疗组优于对照组；两组间症候疗效及临床症候症状改善均有显著差异（P＜0.01），治疗组显著优于对照组。结论：康肾散不但能显著改善慢性肾小球肾炎患者神疲乏力、水肿、纳呆食少、腰痛、面色少华、肌肤甲错或肢体麻木等临床症状，而且能够降低24小时尿蛋白定量，并未发现不良反应。