非变应性鼻炎与变应性鼻炎患者临床特征分析

摘要

目的：比较非变应性鼻炎与变应性鼻炎的临床特征及并发症。方法278例鼻炎患者分为变应性鼻炎组（ AR组）与非变应性鼻炎组（ NAR组）。记录2组的临床症状、疾病严重程度与时间、并发症，比较2组的异同。结果 AR组的鼻部症状、眼部症状、咳嗽出现的频率明显高于NAR组，差异有统计学意义（ P＜0．05）。2组中多为中重度持续性患者，轻度持续性患者的数量最少。 AR组的中重度间歇性患者明显多于NAR组的患者（P＜0．05）。2组出现心血管疾病、下呼吸道并发症患者的构成比差异有统计学意义（ P＜0．05）。 AR组患者的下呼吸道疾病主要为哮喘，人数明显多于NAR组的哮喘患者。2组患者药物过敏史比较差异无统计学意义（ P＞0．05）。结论变应性与非变应性鼻炎是两类不同疾病，其发病机制、临床特征及并发症均存在一定差异。%Objective To compare the clinical features and complications in allergic rhinitis ( AR) and non-allergic rhinitis ( NAR) .Methods Two hundred and seventy-eight patients with rhinitis were divided into the allergic rhinitis group ( or the AR group) and the non-allergic rhinitis group (or the NAR group).Clinical symptoms, severity/course of the disease and complications were recorded, and then, similarities and differences in the above data were compared between the two groups.Results Nasal symp-toms, ocular symptoms, cough frequency in the patients of the AR group were obviously higher than those of the patients in the NAR group, all with statistical significance (P<0.05).The Patients with severe persistent symptoms constituted the vast majority in the 2 groups, and patients with mild symptoms were quite few.Patients with moderate and severe intermittent symptoms in the AR group were significantly more than those in the NAR group, with statistical significance (P<0.05).Statistical significance could be noted in the ratio of patients with cardiovascular disease and lower respiratory tract complications between the two groups (P<0.05).For the pa-tients in the AR group, main lower respiratory tract disorder was asthma, and the number of patients with asthma was significantly more than that of the patients in the NAR group.No statistical difference could be seen in the drug allergy, when comparisons were made be-tween the 2 groups (P>0.05).However, statistical significance could be noticed in the ratio of patients with cardiovascular disease and lower respiratory tract complications (P>0.05).Conclusion Allergic rhinitis and non-allergic rhinitis are two different diseases, and pathogenesis, clinical features and complications are quite different.At present, there are no clear definitions for the differentiation of the disease.Therefore, further research is required, so as to improve diagnosis and treatment of the disease.