妊娠期抗生素使用情况调查及分析

摘要

Objective:To survey current situation of antibiotics use during pregnancy ,which will provide reference for the rational use of drugs during pregnancy .Methods:To collect data of 1010 cases who deliveried in our hospital ,and to analysis situation of antibiotics use during pregnancy and related factors .Results:225 cases(22 .3％ )have used at least one antibiotics during pregnancy .The most commonly used drugs were second-generation cephalosporins 92 cases (40.9％ ) ,first-generation cephalosporins 62 cases (27 .6％ ) ,Penicillins 41 cases (18 .2％ ) ,other drugs 30 cases (13.3％ ) ,successively .People who have pregnancy complications(OR=7 .3 ,95％ CI:5 .0～10 .7) ,hospitalization dur-ing pregnancy(OR=3 .4 ,95％ CI:2 .2～5 .3) would be at higher risk to use antibiotics during pregnancy .Conclusion:Pregnant women commonly used antibiotics in pregnancy .Pregnant women with pregnancy complications and hospitali-zation during pregnancy are at higher risk of using antibiotics .%目的:初步了解妊娠期抗生素使用情况及影响因素 ,为孕期合理使用抗生素提供参考.方法:收集我院分娩的1010名产妇资料 ,分析妊娠期抗生素使用情况及影响因素.结果:225例(22 .3％ )产妇在孕期至少使用一种抗生素.妊娠期最常用抗生素依次为二代头孢菌素 92 例(40 .9％ )、一代头孢菌素 62 例(27 .6％ )、青霉素类药物 41 例(18.2％ ) ,其他药物30例(13 .3％ ).有妊娠并发症(OR=7 .3 ,95％ CI:5 .0～10 .7)、孕期住院(OR=3 .4 ,95％ CI:2 .2～5 .3)的孕妇在妊娠期间使用抗生素的风险更高.结论:妊娠期使用抗生素常见 ,有妊娠并发症、孕期住院等因素的孕妇妊娠期使用抗生素风险更高.