首页> 中文期刊> 《医学影像学杂志》 >肺外炎性肌纤维母细胞瘤的影像学表现

肺外炎性肌纤维母细胞瘤的影像学表现

         

摘要

Objective To analyze the imaging of extrapulmonary inflammatory myofibroblastic tumor(IMT)and to improve the knowledgement of it.Methods 6 cases of IMT were confirmed by pathology,in which 5 cases underwent immunohistochem-istry examination.The imaging appearances were retrospectively discussed.Results All cases were solitary and occured in pleu-ra,right lower quadrant,spleen,liver,vocal cord and underjaw,respectively.6 cases underwent CT scan and 4 cases underwent enhanced scan.1 case underwent MRI plain and contrast scan.CT demonstrated soft tissue mass in 5 cases with well defined boundary,regular shape and slight or moderate enhancement.1 case demonstrated slightly thick vocal cord.Necrosis without en-hancement can be seen in the center of spleen IMT.The right lower quadrant lesion appeared equal signal on T 1WI,lower signal on T2WI,and high signal on DWI.The tumor tissue consisted of spindle fiber cells with a large amount of inflammatory cell infil -tration.SMA expressed positively on immunohistochemistry.Conclusion IMT appeared no specificity in imaging, pathology should be done to confirm it.But,imaging can reveal the lesion itself and relationship to the surrounding tissue.It has a certain value in prognosis and follow-up.%目的 分析肺外炎性肌纤维母细胞瘤的影像学表现,提高对该病的认识.方法 搜集经手术病理确诊的肺外炎性肌纤维母细胞瘤6例,其中5例行免疫组织化学检查.6例均行CT检查,其中4例行CT增强,1例行MRI平扫+增强检查,回顾性分析其影像学表现特点.结果 6例病灶均单发,分别位于胸膜、右下腹、脾、肝、声带、下颌.CT表现:1例位于声带仅表现为声带稍增厚,其余5例均见软组织肿块,边界尚清,形态尚规则,轻中度强化.脾内病灶可见液化坏死无强化区.右下腹病灶MRI表现为T1WI等信号,T2WI稍低信号,DWI明显高信号.病理示瘤组织由梭形纤维细胞组成,伴大量炎性细胞浸润,免疫组化SMA阳性表达.结论 炎性肌纤维母细胞瘤影像学表现无特异性,确诊仍需病理学检查,但影像学检查可显示病灶本身及周围情况,对患者预后及随访有一定作用.

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