By analyzing current situation of the Caihai Wetland, combining with '3S' technology, theory of ecosystem health, landscape ecology theory, applying the model of Pressure–State–Response, this paper assessed dynamic changes of ecological frangibility of the Caohai Wetland in Guizhou in 1992, 2000 and 2013. The results showed that the wetland ecosystem had sound principal functions, but also witnessed different degrees of degradation. The ratio of basic complete ecosystem landscape area in the Caohai Wetland reduced from 70.56% in 1992 to 66.26% in 2013, and the ratio of destructed landscape area increased from 12.11% in 1992 to 13.38% in 2013.
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