Objective To discuss the clinical efficacy and nursing points of Curosurf combined with nasal continuous positive airway pressure (NCPAP) on children with neonatal respiratory failure.Methods Children with neonatal respiratory failure were randomly divided into the control group and the treatment group. Children in control group were treated with NCPAP and in treatment group were given Curosurf combined with NCPAP. The blood gas indexes and clinical efficacy were recorded and analyzed before and after treatment.Results The total effective rate in treatment group (88.89%) was significantly higher than that in control group (77.78%) after treatment for 48 hours ( <0.05) . Compared with children in control group, the blood gas indexes of children in treatment group were significantly higher after treatment ( <0.05) . Conclusion The methods of Curosurf combined with NCPAP and careful nursing can significantly improve clinical efficacy in the treatment of neonatal respiratory failure.%目的：探讨单纯持续鼻塞正压通气（NCPAP）联合固尔苏治疗新生儿呼吸衰竭的疗效及其护理要点．方法对照组，患儿给予单纯NCPAP治疗；治疗组，患儿在对照组的基础上联用固尔苏治疗．结果治疗组患儿经治疗48 h后，配合细致全面的护理，总有效率明显优于对照组（88.89％vs 77.78％，＜0.05）；治疗组患儿各项血气指标较对照组明显改善（＜0.05）．结论 NCPAP联用固尔苏配合细致全面的护理可明显提高治疗新生儿呼吸衰竭疗效．
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