CLE Peptides in Plants:Proteolytic Processing,Structure-Activity Relationship,and Ligand-Receptor Interaction

摘要

Ligand-receptor signaling initiated by the CLAVATA3/ENDOSPERM SURROUNDING REGION (CLE) family peptides is critical in reg-ulating cell division and differentiation in meristematic tissues in plants.Biologically active CLE peptides are released from precursor proteins via proteolytic processing.The mature form of CLE lig-ands consists of 12-13 amino acids with several post-translational modifications.This review summarizes recent progress toward un-derstanding the proteolytic activities that cleave precursor proteins to release CLE peptides,the molecular structure and function of mature CLE ligands,and interactions between CLE ligands and cor-responding leucine-rich repeat (LRR) receptor-like kinases (RLKs).