Differential requirement of BAK1 C-terminal tail in development and immunity

摘要

BRI_1-ASSOCIATED RECEPTOR KINASE 1(BAK_1) plays critical roles in plant developmental and immune signaling pathways. BAK_1 and a large number of leucine-rich repeat receptor-like kinases(LRR-RLKs)harbor a mysterious carboxyl-terminal tail(CT) beyond their kinase domain. In this study we analyzed the biological significance of this CT region using a unique bak_1 mutant allele which causes deletion of the CT region. We showed that BAK_1 CT promotes its kinase activity and is required for pathogen-associated molecular pattern(PAMP)-triggered immunity, but it is dispensable for brassinosteroid responses and BAK_1/BKK_1-inhibited cell death signaling. Therefore the BAK_1 C-terminal tail is differentially required for its functions in development and immunity.