Objective:To investigate the changes of inflammatory factors and immune function indexes in children with infectious pneumonia,to analyze the relationship between the level of indicators and the severity of the disease.Methods:16O children with infectious pneumonia were selected as the observation group included bacterial pneumonia group(n=98),myco-plasma pneumonia group(n=32)and viral pneumonia group(n=3O),according to the severity of the disease,they were di-vided into mild group(n=1O5)and severe group(n=55),at the same time 1OO cases of healthy children in the same period were selected as control group,the levels of inflammatory factors and the indexes of immune function were compared between the groups and different courses of disease.Results:Compared with the control group,the levels of hs-CRP and PCT in the ob-servation group were significantly increased,and in the observation group,the bacterial pneumonia group of hs-CRP and PCT levels were significantly higher than those in mycoplasma pneumonia group and viral pneumonia group,compared with the viral pneumonia group hs-CRP level,the level in the mycoplasma pneumonia group was significantly increased(P< O.O5);The comparison of immune function index,the observation group CD3+,CD4+and CD4+/CD8+levels[(66.32 ± 8.61)%,(36.51 ± 6.26),(1.21 ± O.29)]were significantly lower than those of the control group,the level of CD8+(26.34 ± 5.11)% was sig-nificantly higher than the control group(22.75 ± 3.88)%(PO.O5);The severe group hs-CRP,PCT and CD8+levels were significantly higher than the mild group,and the levels of CD3+,CD4+and CD4+/CD8+were significantly de-creased(PO.O5);与轻症组相比,重症组 hs-CRP、PCT 及CD8+水平水平均显著升高,CD3+、CD4+及CD4+/CD8+水平均显著降低,差异有统计学意义(P展开▼
