A meta-analysis of randomized controlled trials of acupuncture bloodletting for shingles

摘要

Objective:To systematically evaluate the clinical efficacy of acupuncture bloodletting therapy for herpes zoster.Methods:The computer searched the CNKI,WanFang,VIP,CBM,PubMed,and Cochrane Library databases.The time limit was from the establishment of the database to December 31,2019.Relevant literatures on randomized controlled trials of spinal bloodletting for shingles were retrieved.Data were extracted and quality evaluated based on the Cochrane bias risk assessment method.Meta analysis was performed using Rev Man5.3 and Stata15 statistical software.Results:(1)A total of 21 Chinese literatures were included,with a total of 1,533 patients;(2)Meta-analysis was performed using a fixed effect model,and the results showed that the total effective rate of the experimental group(OR=5.11,95%CI:(3.48,7.50),Z=8.33,P<0.00001)is better than the control group,the difference is statistically significant;(3)VAS score analysis using a random effects model(MD-2.23,95%CI(-2.46,-1.99),p<0.0001)(4)The incidence of sequela neuralgia was analyzed using a random effects model(OR=0.21,95%CI:(0.09,0.51),Z=3.48,P=0.0005).Conclusion:The effect of spinal bloodletting on the treatment of shingles and VAS scores,symptomatic relief,and the incidence of sequela neuralgia have advantages.