Success rate and trauma degree of three minimally invasive operating methods URL, MPCNL and RLU for upper ureteral calculi

摘要

Objective:To analyze the success rate and trauma extent of three minimally invasive operating methods URL, MPCNL and RLU for upper ureteral calculi.Methods: According to different operating methods, 138 patients with upper ureteral calculi were divided into transurethral ureteroscopic lithotripsy (URL) group (n=48), minimally invasive percutaneous nephrolithotomy (MPCNL) group (n=50) and retroperitoneal laparoscopic ureterolithotomy (RLU) group (n=40). Differences in one-time calculus removal success rate, postoperative trauma degree and so on were compared among the three groups after treatment.Results:One-time stone-free rate of MPCNL group and RLU group were significantly higher than that of URL group. Inflammatory factors TNF-α PCT, IL-1β and IL-8 content in serum of RLU group and URL group were lower than those of MPCNL group; immunoglobulin and complement IgG, IgM, IgA, C3 and C4 content in serum were significantly higher than those of MPCNL group; endocrine hormones NE, ACTH and Cor content in serum were lower than those of MPCNL group; pain mediatorsβ-EP, NGF, CGRP, 5-HT, SP and PGE2 content in serum were lower than those of MPCNL group.Conclusions:RLU has the advantages of both high efficiency in calculus removal and small trauma, and it is the ideal operating method for clinical treatment of upper ureteral calculi.