Effect of phacoemulsification combined with intraocular lens implantation on diabetic cataract treatment

摘要

Objective:To observe the effect of phacoemulsification combined with intraocular lens implantation on inflammatory factors, oxidative stress reaction and the hemorheology in patients with diabetic cataract, for helping clinical treatment of patients with diabetic cataract. Methods: A total of 160 diabetic cataract patients in our hospital were selected and randomly divided into observation group and control group, each group were 80 cases, control group was treated with conventional therapy, observation group was treated with phacoemulsification combined with intraocular lens implantation based on conventional therapy, the changes of inflammatory factors, oxidative stress reaction and the hemorheology were detected before and after treatment.Results: The difference of inflammatory factors, oxidative stress reaction and the hemorheology in the two groups before treatment was not statistically significant (P>0.05). Inflammatory factors (IL-2, IL-6, hs-CRP and TNF-α), MDA in both groups after treatment significantly increased compared with that before treatment.; oxidative stress reaction parameters (CAT, SOD, GSH-Px), hemorheology parameters (WHV, WLV, PV) in both groups after treatment significantly decreased compared with that before treatment. Changes in PCV and FIB in two groups after treatment was not statistically significant compared with that before treatment (P>0.05). MDA, Inflammatory factors (IL-2, IL-6, , hs-CRP and TNF-α) and hemorheology parameters (WHV, WLV, PV) in observation group after treatment decreased more significantly than that in control group (P0.05). Conclusions:Phacoemulsification combined with intraocular lens implantation could improve inflammatory factors, oxidative stress reaction parameters and hemorheology parameters in diabetic cataract patients, and help clinical treatment of diabetic cataract patients.