Changes and clinical significance of liver function and myocardial zymogram in children with rotavirus enteritis

摘要

Objective:To explore the changes and clinical significance of liver function and myocardial zymogram in children with rotavirus (RV) enteritis.Methods:A total of 70 children with RV enteritis who were admitted in our hospital were included in the study and served as the observation group. The liver function and myocardial zymogram before and after treatment were detected. The proportion of RV enteritis children with liver and myocardial damage was calculated. The effect of dehydration on the liver function and myocardial zymogram in children with RV enteritis was analyzed. A total of 65 children with non-RV enteritis who were admitted in our hospital at the same stage were served as the control group.Results:The serum ALT, AST, CK, CK-MB, LDH, andα-HBDH levels, and liver myocardial damage children proportion in the observation group were significantly higher than those in the control group (P<0.05). The serum ALT, AST, CK, CK-MB, LDH, andα-HBDH levels in the observation group were significantly elevated with the acceleration of dehydration degree (P<0.05). In the observation group, 45 children had liver and myocardial damage, whose ALT, AST, CK, CK-MB, LDH, andα-HBDH levels after treatment were significantly reduced when compared with before treatment (P<0.05).Conclusions:Early detection of liver function and myocardial zymogram can accurately reflect the condition in children with RV enteritis, which can provide an evidence for the formulation of clinical treatment protocol.