Assessment of postoperative fracture healing, trauma degree and neurological functional recovery in thoracolumbar burst fracture patients with or without screw placement in injured vertebra

摘要

Objective:To study the postoperative fracture healing, trauma degree and neurological functional recovery in thoracolumbar burst fracture patients with or without screw placement in injured vertebra.Methods:Patients with single-segment thoracolumbar burst fracture who received posterior short-segment pedicle screw fixation in our hospital between May 2012 and December 2014 were selected as the research subjects and divided into screw placement group (group A) and no screw placement group (group B) according to the screw placement in injured vertebra or not, fracture healing was followed up, the injured vertebral anterior height and Cobb's angle were measured, and serum pNF-H, HSP70, NSE, S100β, GFAP, IL-1β, IL-6, IL-8, IL-10, TNF-α and MPO content of determined 3 d after operation.Results: Injured vertebral anterior height of two groups 1 week, half a year and 1 year after operation were significantly higher than those before operation and Cobb's angle were significantly lower than those before operation, injured vertebral anterior height of two groups half a year and 1 year after operation were significantly lower than those 1 week after operation and Cobb's angle were significantly higher than those 1 week after operation, injured vertebral anterior height of group A half a year and 1 year after operation were significantly higher than those of group B and Cobb's angle were significantly lower than those of group B; 3 d after operation, serum pNF-H, HSP70, NSE, S100β, GFAP, IL-1β, IL-6, IL-8, IL-10, TNF-α and MPO content were not significantly different between two groups of patients.Conclusion:Screw placement in injured vertebra in posterior short-segment pedicle screw fixation treatment of thoracolumbar burst fracture can reduce the loss of vertebral height and kyphosis correction and improve long-term spinal nerve function without increasing the surgical trauma.