Effect of probiotics combined with zinc preparation treatment on serum related indicators in children with protracted diarrhea

摘要

Objective:To analyze the effect of probiotics combined with zinc preparation treatment on serum related indicators in children with protracted diarrhea.Methods: A total of 70 children with protracted diarrhea were included in the study and randomly divided into observation group and control group (n=35). Control group accepted probiotics treatment alone, observation group received probiotics combined with zinc preparation treatment, and differences in serum related indicator values were compared between two groups.Results:Serum NO, MDA, GAS and sIL-2R values of observation group after treatment were lower than those of control group, and SOD, RGE2, IgA, IgM, IgG and zinc values were higher than those of control group (P<0.05); serum inflammatory markers IL-6, IL-8, hs-CRP, PCT and HMGB1 values were lower than those of control group (P<0.05).Conclusions:Probiotics combined with zinc preparation treatment can optimize the overall conditions and restore homeostasis in children with protracted diarrhea, and has positive clinical significance.