Effect of adenosine cyclophosphate combined with vitamin C on cellular immune function of children with viral myocarditis

摘要

Objective:To investigate the curative effect of adenosine cyclophosphate combined with vitamin C on children with viral myocarditis andon cellular immune function.Methods:A total of96 cases of children with viral myocarditis were randomly divided into control group and observation group, 48 cases in each. The control group received routine treatment for viral myocarditis. The observation group received routine treatment for viral myocarditis as well as vitamin C and adenosine cyclophosphate.Results:The total effective rate of observation group 89.59% was higher than that of control group 64.58%, and differences were statistical significant. The electrocardiogram total effective rate of observation group 91.67% was higher than that of control group 68.75%, and differences were statistical significant. After treatment, the level of CD3+ (65.09±10.35)%, the level of CD4+ (42.93±6.22)%, the level of CD8+ (29.55±4.87)% and the level of NK (47.37±8.52)% of observation group were higher than the level of CD3+ (51.85±9.33)%, the level of CD4+ (35.18±5.73)%, the level of CD8+(24.46±4.03)% and the level of NK (35.64±7.72)% of control group, and differences were statistical significant. After treatment, myocardial enzyme indexes lactate dehydrogenase (329.65±19.76) U/L, creatine phosphate kinase (126.36±12.92) U/L, hydroxybutyrate dehydrogenase (271.68±14.73) U/L, glutamic oxaloacetic transaminase (31.22±3.76) U/L and creatine kinase (185.28±13.83) U/L of observation group were lower than lactate dehydrogenase (348.06±20.51) U/L, creatine phosphate kinase (163.19±13.15) U/L, hydroxybutyrate dehydrogenase (305.50±16.42) U/L, glutamic oxaloacetic transaminase (37.87±4.07) U/L and creatine kinase (202.79±15.47) U/L of control group, and differences were statistical significant. After treatment, heart function indexes CI, FS and EF levels of observation group were higher than those of control group, and differences were statistical significant.Conclusions:Adenosine cyclophosphate combined with vitamin C treatment of children with viral myocarditis has exact curative effect, and it can improve cardiac function of patients and improve immune function.