无对照二分类资料的Meta分析方法及Stata实现

摘要

目的 介绍无对照二分类资料Meta分析方法及在Stata软件中的操作步骤.方法 首先介绍3种数据类型无对照二分类资料Meta分析的原理及方法,再用Stata软件对3个实例数据进行Meta分析.结果 无对照二分类资料Meta分析的关键是选择服从正态分布或可转化为正态分布的指标.3个实例数据经正态转换后进行Meta分析,结果与原文一致.结论 Stata软件可实现无对照二分类资料(含患病率、发病密度和比值)的Meta分析,操作简单,实用性强.%Objective To introduce the method of meta-analysis for non-comparative binary outcomes and its realization in Stata. Methods We first introduced principles and methods of meta-analysis for three types of non-comparative binary outcomes, and then replicated results of three published meta-analyses in Stata. Results The key point of doing these meta-analyses was to choose the effect size indices which were of normal distribution or could be-transformed into normal distribution. The replicated results were consistent with the original literatures. Conclusions Meta-analyses for three types of binary outcomes, including prevalence, incidence density, and odds, could be done in Stata conveniently.