三维斑点追踪成像评价脑利钠肽在急性前壁心肌梗死治疗中的价值

摘要

Objective To analyze the clinical value of three-dimensional speckle tracking imaging in assessment of brain natriuretic peptide in acute anterior myocardial infarction.Methods Seventy-four cases of acute anterior wall myocardial infarction patients were randomly devided into the control group and the observation group,37 cases in each group.The control group was treated with emergency PCI,the observation group was treated with brain natriuretic peptide by intravenous injection based on the emergency PCI.Left ventricular wall in 17 segment longitudinal strain,circumferential strain,radial and area strain were compared between two groups before and after 1 month treatment by three-dimensional speckle tracking imaging technique. Results After 1 month treatment,there were significant statistical difference in the 17 segment of left ventricular wall longitudinal strain,circumferential strain,radial strain and the area of the left ventricular wall between control group and observation group(all P<0.05). Conclusion Application of brain natriuretic peptide in patients with acute anterior wall myocardial infarction can effectively improve the myocardial strain capacity,it can improve left ventricular mechanical function in a great extent.%目的 应用三维斑点追踪成像(3D-STI)评价脑利钠肽在急性前壁心肌梗死治疗中的临床价值.方法 将74例急性前壁心肌梗死患者随机分为对照组和脑利钠肽治疗组,每组各37例,对照组行急诊经皮冠状动脉介入治疗,脑利钠肽治疗组在此基础上给予药物脑利钠肽静脉推注治疗.采用3D-STI技术对两组患者治疗前及治疗后1个月左室壁17节段长轴应变、圆周应变、径向应变及面积应变进行比较分析.结果 治疗1个月后,脑利钠肽治疗组患者左室壁17节段长轴应变、圆周应变、径向应变及面积应变均较对照组相应节段有所升高,差异均有统计学意义(均P<0.05).结论 脑利钠肽可有效改善急性前壁心肌梗死患者心肌的应变能力,极大程度上提高左室机械功能.