Objective To investigate the curative effect of Bronchoalveolar Lavage in treating elderly patients with pulmonary inflection in high altitude area.Methods 42 cases of control group were given antiotic and comprehensive therapy,42 cases of lavageing group were given bronchoalveolar lavage and injecting drug on the base of antiotic and comprehensive therapy, bronchoalveolar lavage was given to the treatment group 2 ～3 times per week for 2 weeks.Results In the lavaging group,31 cases(73.8％ )had marked effect,7 cases( 16.7％ )had effect,and 4 cases(9.5％ )had no effect,total effective rate was 90.5％ ,while in the control group, 18 cases(42.9％ )and had marked effect,9 cases(21.4％ )had effect,and 15 cases(35.7％ )had no effect,total effective rate was 64.3％.There significant difference between the total effective rate of the two groups( x2 = 8.182 ,P ＜0.01 ).The positive rate of bacterial cultures of lavage fluid in the lavaging group (90.5 ％ ) was significantly higher than that in sputum cultures of control group (47.6％, x2 = 10.984, P ＜ 0.01 ).Conclusion The mathod of treating elderly patients with pulmonary inflection by bronchoalveolar lavage is safe and effective in high altitude area.%目的 观察支气管肺泡灌洗在高原地区老年肺部感染患者治疗中的应用价值.方法 对照组42例患者给于抗感染及综合治疗;灌洗组42例患者在抗感染及综合治疗的基础上给于支气管肺泡灌洗,每周2～3次,共2周.结果 灌洗组42例中显效31例(73.8%)、有效7例(16.7%)、无效4例(9.5%),总有效率90.5%;对照组42例中显效18例(42.9%)、有效9例(21.4%)、无效15例(35.7%),总有效率64.3%,两组总有效率比较差异非常显著(χ2=8.182,P＜0.01).灌洗组肺泡灌洗细菌培养阳性率(90.5%)显著高于对照组痰液细菌培养阳性率(47.6%),(χ2=10.984,P＜0.01).结论 支气管肺泡灌洗在老年肺部感染中不仅能获得准确的病原菌,为临床选择敏感抗生素提供依据,是高原地区老年肺部感染治疗中一种安全、有效的辅助治疗方法.
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