Objective To investigate the related factors of children with asthma, in order to induct the valid treatment in clinic. Methods 137 children with asthma were selected as the observation group, and 113 children without asthma as the control group. Questionnaires, examinations and asthma history analysis were used to determine the correlative factors for asthma children. Results The survey found that there was a significant difference in history of allergic diseases, acute respiratory infection, breast feeding, passive smoking, harmful gases history and pet own-ership between the two groups(P <0. 05). According to logistic regression analysis, it found that heredofamilial asthma(OR=2. 353, P=0. 001), acute respiratory infection(OR=1. 262, P=0. 004), and history of allergic diseases(OR=5. 527, P=0. 003)were the related factors causing incision infection, and breast feeding(OR=0. 429, P=0. 017)was the protective factor. Conclusion Children with asthma attack causes by many factors. Ac-cording to the relevant factors, we should control and correct the risk factors of children asthma, advocate breast feed-ing. There is a great significance to prevent and control of asthma in children.%目的 对照分析儿童哮喘急性发作的危险因素,为临床诊治提供依据.方法 选择支气管哮喘患儿137例作为观察组与同期门诊113例健康体检患儿作为对照组,对两组资料进行对比分析,寻找发作的危险因素.结果 对比两组患儿发现哮喘家族史、被动吸烟史、呼吸道感染史、有害气体接触史、母乳喂养、过敏性疾病史方面比较,差异有显著统计学意义(P<0.05);Logistic多因素回归分析发现哮喘家族史(OR=2.353,P=0.001)、呼吸道感染史(OR=1.262,P=0.004)、过敏性疾病史(OR=5.527,P=0.003)是小儿支气管哮喘发作的危险因素,而母乳喂养(OR=0.429,P=0.017)是保护性因素.结论 小儿哮喘发作是多因素综合作用的结果,应当根据相关因素采取有针对性措施,尽可能母乳喂养,对小儿哮喘的预防和控制具有重要作用.
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