重症手足口病早期实验室检查结果分析

摘要

目的 分析比较手足口病轻、重症病例的初期实验室检查指标,为治疗提供临床依据.方法 对2010年4月～2010年8月期间本院门诊及病房收治的112例手足口病分为轻症型组(n=106)和重症型(n=6),对2组的临床资料、初期实验室检查指标进行回顾性分析.结果 2组患儿的白细胞计数、血糖及肌酸激酶同工酶测定结果显示,重症型组患儿以上3个指标的水平明显高于轻症型患儿,差异有统计学意义(P<0.01); 2组患儿检验异常率比较结果显示,重症型患者中白细胞计数升高、血糖水平升高、肌酸激酶同工酶升高的患者比率明显高于轻症型患者,差异有统计学意义(P<0.05).结论 白细胞计数、血糖及肌酸激酶同工酶测定可作为删选轻症和重症手足口病的重要依据;实验室检查指标可以作为筛查重症手足口病的预警指标.%Objective To analyze and compare the early laboratory indicators in mild, severe cases of hand - foot - and - mouth disease, to provide the clinical basis for the therapy.Methods During April 2010 and August 2010, 112 hand-foot- and- mouth disease patients from our hospital were divided into mild type group (n = 106) and severe type group( n = 6).Clinical data on two groups, the initial laboratory indexes were analyzed retrospectively.Results Both groups of children with white blood cell count, blood glucose and creatine kinase measurement showed that children in severe type group had higher levels of the three indicators than children in mild type group, there was statistically significant difference(P＜ 0.01).Abnormal rate between two groups of children tested showed elevated ratio of white blood cells, blood sugar and creatine kinase were more obvious in severe type group than the patients in mild type group.The difference was statistically significant (P＜0.05 or P＜ 0.01).Conclusion White blood cell count, blood glucose and creatine kinase measurement are important indicators to differentiate mild and severe hand - foot -mouth diseases.Laboratory indexes can be used as primary screening indicators to determine severe hand- foot - and - mouth disease.