目的 探讨血清超敏C-反应蛋白(Hs-CRP)、胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白-胆固醇(LDL-C)与2型糖尿病并发动脉粥样硬化的关系.方法 150例糖尿病患者(实验组)及50例健康对照者(对照组)均采用免疫比浊法测定Hs-CRP,氧化酶法测定TG、TC、一步法测定LDL-C水平,并进行相关性分析.结果 实验组Hs-CRP、TG、TC、LDL-C较对照组明显升高(P<0.001),血糖控制不良组(C组)中Hs-CRP明显高于血糖控制良好组(A组)和血糖控制一般组(B组)(P<0.01),B组高于A组(P<0.01)且与TG、TC、LDL-C正相关.结论 Hs-CRP、TG、TC、LDL-C与2型糖尿病并发动脉粥样硬化密切相关,可作为风险预测指标预测2型糖尿病并发症出现.%Objective To probe into the relationship between high - sensitivity C - reactive protein ( 11s - CRP ), cholesterol ( TC ), tri-glyceride ( TG ), low - density lipoprotein cholesterol ( LDL - C ) and the emergence of atherosclerosis in patients with type 2 diabetes. Methods 11s - CRP, LDL - C, and TG and TC were detected by immunoturbidimetry, one - step method and oxidase method respectively in 150 diabetes patients ( experimental group ) and 50 healthy controls ( control group ). Results The levels of 11s - CRP, TG, TC and LDL - C were significantly higher in experimental group than in the control group ( P < 0. 001 ). The level of 11s - CRP in group C( Poor blood sugar control ) was obviously higher than group B( Blood sugar control general ) and group A( Good blood glucose control )( P <0.01 ) and higher in group B than group A ( P < 0. 01 ) 11s - CRP level was positively correlated with the levels of TG, TC and LDL - C. Conclusion The levels of 11s - CRP, TG, TC and LDL - C are closely related with atherosclerosis in patients with type 2 diabetes, they can be used as risk predictors for type 2 diabetes - related atherosclerosis.
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