D-二聚体、纤维蛋白原、癌胚抗原与SCLC患者生存期的关系

摘要

[ABSTRACT]Objective: To investigate the relationships between D-dimer, ifbrinogen (FIB), carcino-embryonic antigen (CEA) and survival time in patients with small cell lung cancer (SCLC).Methods: The clinical data of 78 SCLC patients were collected and retrospectively analyzed the relationships between D-dimer, FIB, CEA level and survival time of SCLC patients.Results:The survival time of SCLC patients was connected with D-dimer, FIB and CEA level (P<0.05). Cox regression analysis showed that D-dimer level was an independent factor that inlfuence survival time of SCLC patients (P<0.05).Conclusions: D-dimer, FIB and CEA level are relevant to survival time of SCLC patients. D-dimer level can be used as a prognostic indicator for SCLC patients.%目的：：探讨D-二聚体、纤维蛋白原(FIB)、癌胚抗原(CEA)水平与小细胞肺癌(SCLC)患者生存期的关系。方法：回顾性分析经病理学确诊的78例SCLC患者的临床资料，分析患者D-二聚体、FIB、CEA水平与生存期的关系。结果：SCLC患者生存期与D-二聚体、FIB、CEA水平有关(P＜0.05)；Cox多因素回归分析结果显示， D-二聚体水平为影响SCLC患者生存期的独立因素(P＜0.05)。结论：D-二聚体、FIB、CEA水平均与SCLC患者生存期有关，其中D-二聚体可作为判定SCLC患者预后的指标。