通过溶液沉析纺丝法制备聚丙交酯-乙交酯(PLGA)纤维,观察纤维的形貌并对其进行XRD和SEM表征.采用纤维温压成形法控制压力和温度得到条形的PLGA材料结合试样断口分析,研究成型压力与温度对PLGA材料的力学性能的影响.研究结果表明:非晶多孔结构的PLGA纤维可通过溶液沉析纺丝的方法获得,其孔径为0.1～ 1.0 μm;压制压力和压制温度对材料的力学性能影响较大,材料的抗弯强度、剪切强度和抗弯模量均随着温度和压力的增大而先增大后降低;在压制压力为105 MPa,压制温度为160 ℃时,试样的力学性能比较理想,此时,其抗弯强度可达到187.3 MPa,剪切强度达到100.1 MPa,抗弯模量达到2.5 GPa,可望作为非承重部位骨折愈合内固定材料.%Solvent spinning method was used to prepare Poly(lactic acid-glycolic acid) (PLGA) fiber. The fiber was observed by X-ray diffractometry (XRD) and scanning electron microscope (SEM). PLGA rectangular materials were fabricated by fiber mild temperature molding and the effects of molding pressure and temperature on the mechanical strength of PLGA were also investigated. The results show that the amorphous PLGA fiber with porous structure (0.1-1.0 μm) is obtained by diluted solvent spinning method and the mechanical properties is affected by pressure and temperature. Bending strength and shearing strength of the samples increase firstly and then decrease with the increase of molding temperature and pressure. While the molding temperature is 160 ℃ and the pressure is 105 MPa, the PLGA materials possess optimal mechanical properties, bending strength, shearing strength and bending modulus 187.3 MPa, 100.0 MPa and 2.5 GPa, respectively. The mild temperature molding PLGA materials are desired to play a grate role in non-bearing internal fixation devices.
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