双针穿刺臭氧注射+等离子射频治疗盘源性腰腿痛的临床研究

摘要

Objective To observe the efficacy and safety of intervertebral disc double needle injection of ozone combined with ablation for the treatment of discogenic low back pain of coblation target through different minimally invasive methods. Methods Totally 120 patients received minimally invasive interventional treatment for lumbar intervertebral disc were randomly divided into 3 groups, Group A received coblation, Group B received double needle injection of ozone, and Group C received both ablation and double needle injection of ozone. Visual analogue scale(VAS), treatment effect, Oswestry disability index(ODI) and complications were evaluated before the treatment, 3 days, 30 days and 90 days after the treatment for all patients. Results The VAS values after treatment in each group significantly decreased, and the difference was statistically significant(P<0. 05), and the VAS value reduction and the therapeutic effect of Group C 30 days and 90 days and the ODI of Group C 90 days after the treatment were much more significant than that of Group A and B(P<0. 05). No significant complication happened during treatment. Conclusion The therapeutic effect of the combination of double needle injection of ozone and coblation was more obvious and lasted longer.%目的：探讨双针穿刺臭氧注射结合低温等离子射频治疗盘源性腰腿痛的有效性和安全性。方法将120例盘源性腰腿痛患者采用数字表法随机分为3组,A组行低温等离子射频,B组行双针穿刺臭氧注射,C组行双针穿刺臭氧注射结合低温等离子射频。评价各组治疗前,治疗后3、30、90 d的视觉模拟评分( visual analogue scale,VAS)、治疗效果、Oswestry功能障碍指数( Oswestry disability index,ODI)及合并症发生情况。结果3组患者治疗后各时间点VAS与治疗前比较,差异有统计学意义( P<0.05),C组治疗后30、90 d VAS和治疗效果优良率及治疗后90 d ODI与A组、B组比较,差异有统计学意义(P<0.05)。各组治疗期间均未发生明显不良反应。结论双针穿刺注射臭氧结合低温等离子射频比单纯低温等离子射频或双针穿刺注射臭氧治疗效果更确切,持续时间更长久。