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Study on relationship between perifollicular blood flow and in vitro fertilization-embryo transfer

机译:卵泡周血流与体外受精-胚胎移植关系的研究

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Objective:To study the relationship between perifollicular blood flow and follicule development,oocyte maturing rate,fertilizing rate,cleaving rate,embryo quality and the outcomes of embryo transfer.Methods:The samples were selected from 66 suffers who underwent in vitro fertilization(IVF)or intracytoplasmic sperm injection(ICSI).Eeach patients' perifollicular blood flow(diameter ≥ 12mm)was estimated on the day of human chorionic gonadotropin(HCG)administration.Results:Among 66 cycles,26(39.4%)cycles resulted in pregnancy.perifollicular blood flow resistance index(RI),peak systolic velocity/end diastasis velocity(S/D)of non-preg-nant group was significantly higher than that of the pregnant group(P 0.05).There were no statistical difference between non-pregnant group and pregnant group in S and D(P > 0.05).There was no correlation between periFollicular blood flow RI and follicular diameter by linear regression analysis.Conclusion:Our study shows that perifollicular blood flow RI and S/D are effective indices of predicting the pregnancy outcome of IVF-ET.
机译:Objective: To study the relationship between perifoUicular blood flow and follicule development, oocyte maturing rate, fertilizing rate, cleaving rate, embryo quality and the outcomes of embryo transfer. Methods: The samples were selected from 66 suffers who underwent in vitro fertilization(IVF)or intracytoplasmic sperm injection(ICSI). Eeach patients' perifollicular blood flow(diameter≥12mm )was estimated on the day of human chorionic gonadotropin(HCG)administration. Results:Among 66 cycles, 26(39.4%) cycles resulted in pregnancy, perifollicular blood flow resistance index(Rl), peak systolic velocity/end diastasis velocity(S/D) of non-preg-nant group was significantly higher than that of the pregnant group (P < 0.004). When RI<0.49, the pregnancy rates, fecundation rates, fertilization rates, metaphase numbers for the of second meiosis oocytes increased evidently(P<0.05), but there were no statistical difference in gonadotropin dosage, cycle frequency, infertility years, ages, estradiol(E2)on the day of HCG administration,numbers of oocyet retrieved and high-quality embryo rates (P > 0.05 ). There were no statistical difference between non-pregnant group and pregnant group in S and D (P>0.05). There was no correlation between periFollicular blood flow RI and follicular diameter by linear regression analysis. Conclusion:Our study shows that perifollicular blood flow RI and S/D are effective indices of predicting the pregnancy outcome of IVF-ET.

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