Generation of monoclonal antibodies against n-3 fatty acid desaturase

摘要

Dear Editor:Omega-3 polyunsaturated fatty acids（n-3 PUFAs）are essential fatty acids for normal cellular functions and have been used for prevention and treatment of many diseases,including coronary heart disease,diabetes,and cancers[1-3].n-3 PUFAs and n-6 PUFAs have been shown to decrease and increase the severity of several human diseases,respectively[4].Unfortunately,mammals have no enzymes to synthesize n-6 and