Serum IL-1β and IL-18 correlate with ESR and CRP in multidrug-resistant tuberculosis patients

摘要

Dear Editor:The emergence of multidrug-resistant tuberculosis(MDR-TB)is bringing new challenges.MDR-TB is caused by Mycobacterium tuberculosis(M.tuberculosis)that is resistant to isoniazid and rifampicin,with or without resistance to other anti-tuberculosis drugs.Approximately 450,000 people developed MDR-TB worldwide in 2012 and an estimated 170,000 people died from the disease^([1]).Bacterial burden is not strictly correlated with disease progression,and several hallmarks of severe tuberculosis suggest that insufficiently