Editorial commentary on the special issue of CRISPR Trends in Biomedical Research

摘要

In 2012,the laboratories of Drs.Emmanuelle Charpentier and Jennifer Doudna reported the repurposing of a bacterial adaptive immune system,known as CRISPR,as a programmable,RNA guided DNA editing system in eukaryotic cells.Over the next 12 months,a tsunami of research papers emerged demonstrating the facile utilization of this newfound genome editing platform in a variety of cell types and animal models.Since 2013.