Human parvovirus B19-associated hematopathy in HIV disease：need for clinicopathological revisit

摘要

Persons living with HIV infection occasionally suffer from anemia due to varying causes.These include the use of zidovudine,malnutrition especially vitamin B12and iron deficiency,opportunistic infections by Mycobacterium tuberculosis,Pneumocystis jiroveci,and direct hematological effects of HIV infection itself within the marrow microenvironment.Persistent Parvovirus B19(B19V)infection is a clinically important and treatable etiology of anemia in HIV-infected persons.B19V is known to show singular tropism and