Department of Neurology and Psychiatry Hospital Medical College University of Science and Technology 430030;
Department of Neurology Downstate Medical Center 11226;
Department of Anesthesiology and Perioperative Medicine First Affiliated Hospital of Nanjing Medical University 210029;
Department of Pharmacology of Basic Medical Sciences University 200032;
amyotrophic lateral sclerosis; cognitive decline; gut microbiota; fecal metabolites; bile acids;