Medicinal importance, pharmacological activities, and analytical aspects of aloin：A concise report

摘要

Natural products such as pure phytoconstituents and plant extracts offer limitless opportunities for the new drug development due to its unmatched chemical diversity.Plants play an important role in the medicinal preparations for both preventive and curative purpose.Some of the currently available drugs i.e. aspirin, digitalis, anti-malarial(quinine) and anti-cancer(vincristine, vinblastine) were derived from the plant sources.Aloin(C21H22O9), a yellow colour compound is a mixture of two diastereoisomers, aloinA and aloinB.Aloin is an anthroneC-glucoside having molecular weight418, and it is the main phytoconstituents of aloes.Aloin is used for various pharmacological purposes such as laxative agent.It is also used as ingredients of various laxative pharmaceutical preparations.So far, varieties of analytical methods have been developed for the estimation of aloin in aloes product, which are mainly based onHPLC andTLC techniques.In the present review, pharmacological activities and analytical aspects of aloin were highlighted along with some useful tissue culture techniques.This review could be helpful to the researcher for the investigation of new molecule from aloin in the future.