45例结核菌素试验阳性的结节性红斑的诱因及特点分析

摘要

Objective Through treating with antituberculoties and glucocorticoids, explore the pos-sible motivation and clinical features of erythema nodosum in tuberculin (PPD) test-positive patients Methods Clinical and laboratory data of 45 cases of erythema nodosum were retrospective analyzed, Results 45 patients had typical erytbema nodosum lesions and PPD test-positive or strong positive (100%). According to the chest X-ray examination, 6 cases (13.4%) were with pulmonary tuberculosis, 4 cases(8.9%) with lymph node nuclear, 4 cases (8.9%) with pleurisy, 8 cases (17.8%) with lung shadow foci and 23 cases (51%) have no abnormalities. The results of experimental examination showed that 32 cases were with faster blood sedimentation rate, 2 cases with anti-"O" positive, three cases with IgG higher than the normal, 2 cases with rheumatoid factor positive, one case expectoration bacterium film preparation positive and the rest were all negative. Conclusion The etiology of erythema nodosum was complex and mycobacterium tuberculosis infection was one of the major motivations of tuberculin test-positive erythema nodesum. The treatment of patients with antituberculotics and glucocorticoids could receive good clinical therapeutic effect.%目的 通过扰结核药联合糖皮质激素对结核菌素(PPD)试验阳性的结节性红斑的治疗,探讨结节性红斑可能诱因和临床特点.方法 回顾性分析45例结核菌素试验阳性的结节性红斑的临床和实验室资料.结果 45例患者均具有典型的结节性红斑皮损,PPD试验阳性或强阳性(100%);男女之比为1:4.5,平均年龄34.5岁,平均病程1.2年.45例X光胸片检查合并肺结核6例(13.4%),淋巴结核4例(8.9%),胸膜炎4例(8.9%),肺部阴影灶8例(17.8%),无异常者23例(51%);实验检查:45例中血沉增快32例,抗"O"阳性2例,IgG较正常升高3例,类风湿因子阳性2例,痰菌涂片阳性1例,其余各项均为阴性.结论 结节性红斑病因复杂,结核菌感染是主要诱因,对结核菌素试验阳性的结节性红斑,抗结核药联合糖皮质激素治疗有良好的临床疗效.