家庭护理干预对精神分裂症患者预后的影响

摘要

Objective To explore the effect of family nursing intervention on the prognosis of patients with schizophrenia. Methods 224 patients with schizophreniawere randomly divided into intervention group and control group avrragely. All the patients were given small dose of antipsychotic drugs.But the intervention group was cured by family intervention too. All patients were evaluated with the Brief Psychiatric Rating Scale and the Social Disability Screening Schedule in 6 months, 1 year and 2 years.Compared the recurrence rates between the two groups in 0.5 y's, 1 y's and 2 y's following-up. Results At the end of the study, the patients in the intervention group showed milder illness severity, lower teratogenic and relapse rate in comparison with the control group. Conclusion The family nursing intervention is an effective and feasible rehabilitation of the patients with schizophrenia.%目的 探讨家庭护理干预对精神分裂症患者预后的影响.方法 将符合入组标准的224例精神分裂症患者分为干预组和对照组(每组各112例).两组均服小剂量抗精神病药(折合氯丙嗪为<300 mg/d),其中干预组同时接受家庭干预;于入组时、随访半年、1年、2年时采用简明精神病评定量表(BPRS)、社会功能缺陷筛选量表(SDSS)进行评定,比较两组随访半年、1年、2年复发率.结果 入组时干预组和对照组相比,BPRS、SDSS评分差异均无显著性(P>0.05).家庭护理干预半年、1年、2年后,干预组BPRS评分分别为:(26.80±6.41)分、(28.10±7.52)分、(21.12±5.62)分,对照组的分别为:(31.91±8.53)分、(33.94±9.71)分、(32.01±11.12)分;干预组SDSS评分分别为:(2.34±0.76)分、(1.91±0.82)分、(3.13±2.34)分,对照组的分别为:(6.32±1.07)分、(4.31±1.12)分、(4.52±2.91)分;2组比较差异有极显著性(P<0.01)并持续到随访结束.两组3个时段内的复发例数,干预组均低于对照组,存在显著性差异(P<0.05).结论 家庭护理干预使精神分裂症患者的复发率明显降低.