垂体前叶功能减退症致顽固性低钠血症的临床特征研究

摘要

Objective To analyze the clinical characteristics of refractory hyponatremia induced by hypopituitarism in seventeen patients and to explore the etiology,clinical symptoms,and treatment.Methods The clinical symptoms,laboratory results and etiology were retrospectively analyzed in seventeen patients with refractory hyponatremia caused by hypopituitarism.The clinieal characteristics and therapies were summarized.Results The symptoms were complicated in patients with hyponatremia caused by hypopituitarism.Regular complement of salt and water did not improve and hyponatremia; whereas therapies with glucocorticoids could efficiently treat refractory symptoms and hyponatremia.Conclusions Routine examination of adenohypophysis function should be performed in patients with refractory hyponatremia.Hypopituitarism is an important cause of refractory hyponatremia.Salt should not be complemented blindly to avoid the delay of proper treatment.%目的 分析17例垂体前叶功能减退导致的顽固性低钠血症患者的临床特征,探讨其病因、临床表现及治疗方法.方法 回顾性分析17例垂体前叶功能减退致顽固性低钠血症患者的临床表现、实验室检查及病因,归纳其临床发病特征及治疗方法.结果 垂体前叶功能减退导致的顽固性低钠血症临床症状复杂,常规补钠及补液不能改善低钠血症,予以糖皮质激素治疗后,病情迅速缓解.结论 对于顽固性低钠血症患者应常规进行垂体前叶功能检查,提高对垂体前叶功能减退所导致的低钠血症的认识,从而避免盲目补钠,延误病情.