中西医结合治疗肾虚肝郁型多囊卵巢综合征所致不孕症的效果

摘要

Objective To explore the clinical efficacy of Bushen Tiaojing decoction in patients with kidney defficiency with liver stagnation type barrenness caused by polycystic ovarian syndrome.Methods 176 cases of barrenness caused by polycystic ovarian syndrome in our hospital from October 2011 to January 2016 were randomly divided into control group (88 cases) and observation group (88 cases).The control group was treated with letrozole,and the observation group was treated with Bushen Tiaojing decoction and letrozole.Observed the clinical effect,compared the levels of human chorionic gonadotropin (HCG),estradiol (E2),and progesterone (P),calculated the ovulation rate,pregnancy rate,early abortion rate,and recorded adverse events of the two groups.Results The total effective rate of the observation group was higher than that of the control group (68.2％ vs.44.3％,P＜0.05).There were no statistically significant differences in the levels of HCG,E2,P between the two groups before treatment (P＞0.05);three months later,the levels of HCG,E2,P in the two groups all increased (P＜0.05),the levels of HCG,E2,P of the observation group were higher than those of the control group (P＜0.05).The ovulation rate,pregnancy rate of the observation group were higher than those of the control group,the early abortion rate was lower than that of the control group (P＜0.05).The incidence of adverse reactions of the observation group was lower than that of the control group (P＜0.05).Conclusion Bushen Tiaojing decoction in patients with kidney defficiency with liver stagnation type barrenness caused by polycystic ovarian syndrome can improve clinical effect,the hormone levels in patients,the ovulation rate and pregnancy rate,reduce the early abortion rate and the incidence of adverse reactions,worthy of clinical application and promotion.%目的 探究采用中西医结合治疗肾虚肝郁型多囊卵巢综合征所致不孕症临床疗效观察.方法 选择2011年10月至2016年1月来本院治疗的多囊卵巢综合征所致不孕症患者176例,随机分为对照组和观察组,各88例.对照组采用来曲唑治疗,观察组使用补肾调经汤联合来曲唑进行治疗.观察两组患者的临床治疗效果,内分泌激素人绒毛膜促性腺激素(HCG)、雌二醇(E2)及孕酮激素(P)水平变化、计算并比较两组排卵率、妊振率、早期流产率以及不良反应发生情况比较.结果 观察组的临床治疗疗效68.2％高于对照组44.3％,差异有统计学意义(P＜0.05);治疗前,两组的HCG、E2及P激素水平比较,差异无统计学意义(P＞0.05),治疗3个月后,两组的HCG、E2及P激素水平与治疗前均有所升高,差异有统计学意义(P＜0.05);观察组HCG、E2及P激素水平高于对照组,观察组的排卵率和受孕率明显高于对照组,早期流产率明显低于对照组,差异均有统计学意义(P＜0.05);观察组的不良反应发生率明显低于对照组,差异有统计学意义(P＜0.05).结论 采用中西医结合治疗肾虚肝郁型多囊卵巢综合征所致不孕症可提高临床效果,改善患者激素水平,提高患者排卵率和妊娠率,降低流产率和不良反应发生率,值得在临床上推广及应用.