Objective To investigate the effect of positive thyroid autoantibody on maternal and neonatal prognosis in pregnant women. Methods From March 2015 to November 2016, 80 cases of pregnant women in our hospital were selected, 40 cases of pregnant women diagnosed with positive thyroid autoantibody during pregnancy by blood biochemical examination as the observation group, 40 cases of normal pregnant women as the control group. The perinatal complications (gestational diabetes, pregnancy-induced hypertension, premature birth, stillbirth, and postpartum hemorrhage) of the two groups were compared, the neonatal gestational age, body weight, and 1 min Apgar score of the two groups were compared. Results The total incidence of gestational diabetes, pregnancy-induced hypertension, premature birth, stillbirth, and postpartum hemorrhage of the observation group was significantly higher than that of the control group (P < 0.05). The neonatal gestational age, body weight, and 1 min Apgar score of the observation group were less than those of the control group (P<0.05). Conclusion Pregnant women with positive thyroid autoantibody are prone to pregnancy-related complications, their newborns are prone to premature birth, low birth weight, and neonatal asphyxia, which should be paid more attention to.%目的 探讨甲状腺自身抗体阳性对孕产妇母婴预后的影响.方法 选择2015年3月至2016年11月本院收治孕产妇80例,观察组为血液生化检查确诊存在妊娠期甲状腺自身抗体阳性,对照组为正常孕育妊娠者,每组40例,比较两组孕产妇围产期并发症(如妊娠期糖尿病、妊娠期高血压、早产、死胎及产后出血)发生情况,对比两组新生儿出生胎龄、体重及1 min Apgar评分.结果 观察组妊娠期糖尿病、妊娠期高血压、早产、死胎及产后出血的总发生率显著高于对照组(P<0.05).观察组新生儿出生胎龄小于对照组,出生体重轻于对照组,出生1 min Apgar评分低于对照组(P<0.05).结论 妊娠期妇女甲状腺自身抗体阳性者,容易出现妊娠相关并发症,新生儿容易出现早产、出生体重过低及新生儿窒息,临床应提高重视.
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