Translational medicine is a new concept in international medical ifeld. It integrates experimental research results and clinical guidance into the optimal implementation criteria for promoting the prediction, prevention and treatment of diseases. Based on people’s higher demand for medicine and health, appearance of translational medicine changes the mode of medical research. Evidence-based medicine (EBM) refers to cautious and accurate application of the current best research evidence and combination of the clinician’s professional skills and abundant clinical experience to consider the patients willing and value, consequently making the best diagnostic regimens for patients. Recently, some scholars have begun to question why the patients with the same diagnosis, course of disease and pathological condition have different efifcacies and prognosis after treatment with the same drug. So far, an accurate answer cannot be given based on the research data of EBM to implement translational medicine. The concept of precision medicine is accepted gradually with the development of disease management model. In this study, practice and enlightenment of translational medicine, effect of EBM on translational medicine, EBM limitations as well as emergence and development trend of precision medicine were all reviewed in order to investigate the relationship among translational medicine, EBM and precision medicine.
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