机译：AIM:In order to improve the biocompatibility of intraocular lenses(IOL),the polymethylmethacrylate(PMMA)IOL was modified with F-heparin. METHODS:The PMMA IOL was modified with F ions and heparin by the technique of ion beam combined with low temperature and low pressure plasma.The monkeys(20 eyes)with cataract partly were randomly classified into 2 groups and implanted with PMMA IOL and modified IOL respectively for 180 days.All of the eyes were examined by slit-lamp microscope at postoperative 15,30,60,90,180 days.The extracted IOL was analyzed with computer image analysis,light microscope(LM)and scanning electron microscope(SEM)at postoperative 180 days. RESULTS:The early inflammatory reactions postoperatively include anterior chamber exudation and aqueous cell count. The modified IOL group showed less than the non-modified IOL group.The late foreign body cell reaction that adhered to the surface of non-modified IOL was more predominant.The morphologic and pathological changes of posterior capsule opacification(PCO)in monkeys’ eyes included fibrosis-type, pearl-type and soemmerring’s ring.There was a significant difference between the two groups. CONCLUSION:F-heparin modified IOL has good uveal and capsular biocompatibility.
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