A novel nonsense mutation of GPR143 gene in a Korean kindred with X-linked congenital nystagmus

摘要

<正>Dear Editor,I am Dr.Ungsoo Samuel Kim.from Kim’s Eye Hospital,Konyang University,Seoul,Korea.I write to present a novel mutation of GPR143 in Korean patients with X-linked congenital nystagmus by using exome sequencing.Congenital nystagmus is an inherited ocular disorder that can occur as an X-linked condition.Three genetic loci have been identified for X-linked congenital nystagmus(XLCN):