首页> 中文期刊> 《国际肝胆胰疾病杂志(英文版)》 >Living related liver transplantation for an infant with biliary atresia

Living related liver transplantation for an infant with biliary atresia

         

摘要

Objective: To sum up the preliminary experience inliving related liver transplantation (LRLT).Methods: A 9-month-old male infant with biliaryatresia (BA) who had undergone an unsuccessfulKasai operation was defined as a candidate for LR-LT. The donor was his 30-year-old mother. Her la-teral lobe of the left liver was transplanted into theinfant’s body as the graft. The left branches of theportal vein, left hepatic artery and left hepatic veinof the graft were end-to-end anastomosed to the por-tal vein, hepatic artery proper and hepatic vein ofthe recipient respectively. Biliary drainage was re-established via Roux-en-Y operation.Results: The donor retained her liver function within2 weeks after the operation. Steroid and FK506 wereprescribed in immunosuppressive therapy for the re-cipient. The blood bilirubin level of the infant de-creased to normal 2 weeks after operation. No acuterejection occurred. Biliary leakage in the early peri-od after the transplantation was controlled by drain-age, and E. coli infection was effectively treated withantibiotics. The donor and recipient are in satisfacto-ry condition to the present.Conclusion: LRLT is advisable for children with bili-ary atresia.

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