Detection of anti-HAV and anti-HEV IgM in patients with sporadic acute hepatitis in Beijing between 1995-2000

摘要

Objective: To investigate the age range, liver functiondamage and prognosis of patients with sporadic acutehepatitis A and E in Beijing.Methods: Enzyme immunoassay (EIA) was used todetect anti-HAV and anti-HEV immunoglobulin M(IgM). Serum samples were collected from the pa-tients with sporadic acute viral hepatitis in Beijingfrom January 1995 to June 2000.Results: The total positive rate for anti-HAV and an-ti-HEV IgM was 55.2% (112)in 203 patients with a-cute hepatitis, of whom 22.2% (45 patients) and33.0% (67) were positive for anti-HAV and anti-HEV respectively. The duration of anti-HEV IgMwas 45-60 days and that of anti-HAV IgM was atleast 2-3 months. The patients with acute hepatitis Aand hepatitis E all experienced jaundice and a risingof liver enzyme, but did not develop chronic hepatitisor died.Conclusion: Acute hepatitis A as well as acute hepatitisE plays an important role in sporadic entericallytransmitted hepatitis in Beijing.