NovelH1N1inlfuenzaAvirusinfectioninapatient withacuterejectionafterlivertransplantation

摘要

BACKGROUND: The 2009 H1N1 inlfuenza A virus was ifrst identiifed in April 2009 and rapidly evolved into a pandemic. Recipients of solid-organ transplants have a higher risk for severe infection because of immunosuppression. There are limited reports of 2009 H1N1 inlfuenza in liver transplant recipients, especially in China. METHODS: We present a case of a 48-year-old male liver transplant recipient with 2009 H1N1 inlfuenza A virus. He received therapy for acute rejection after transplantation and was conifrmed with H1N1 virus infection. RESULTS:The patient was started on oseltamivir (75 mg, orally twice daily) and had a benign hospital course, with defervescence and resolution of symptoms within 72 hours. The follow-up chest radiograph after discharge was normal. CONCLUSIONS: The 2009 H1N1 inlfuenza in this hospitalized transplant recipient was relatively mild, and prolonged viral shedding was not noted. Oseltamivir can be a valid measure in immunocompromised individuals.