ANTI SEMA3A ANTIBODIES RESCUE RETINAL GANGLION CELLS FROM CELL DEATH FOLLOWING OPTIC NERVE AXO- TOMY

摘要

Damage to the optic nerve in mammals induces retrograde degeneration and apoptosis of the retinal ganglion cell (RGC) bodies. We have previously shown that semaphorins, axon guidance molecules with repulsive cues, are capable of mediating apopto-