Cirrus HD OCT 检测近视眼黄斑中心凹下脉络膜厚度的研究

摘要

目的：应用 Cirrus HD OCT 测量近视眼黄斑中心凹下脉络膜厚度(SFCT),并探讨其与眼轴、等效球镜的关系。　　方法：纳入正常志愿者70例133眼,分为正视眼组、低度近视组、中度近视组及高度近视组。应用 Cirrus HD OCT测量受检者 SFCT,并评估其与眼轴、等效球镜的关系。　　结果：(1)正常人 SFCT 值为(275.91±55.74)μm,正视眼组、低度近视组、中度近视组及高度近视组 SFCT 值分别为(290.03±34.82)μm,(287.64±51.51)μm,(274.95±56.83)μm,(248.37±67.98)μm；(2)高度近视眼与正视眼 SFCT 值相比差异有统计学意义(P<0.05)；(3) SFCT与眼轴呈高度线性负相关(P<0.01),SFCT 与等效球镜呈高度线性正相关(P<0.01)。　　结论：SFCT 与屈光度有关,且与眼轴呈负相关,与等效球镜呈正相关。%To measure the subfoveal choroidal thickness ( SFCT ) in myopia using Cirrus HD optical coherence tomography ( OCT ), and to explore the relationship between the SFCT, axial length and myopic refractive spherical equivalent. ● METHODS: One - hundred thirty - three eyes of 70 healthy volunteers were recruited, and were divided into emmetropia group, low- degree myopia, middle- degree myopia and high - degree myopia group. SFCT were measured by Cirrus HD OCT, and the relationship between the SFCT, axial length and myopic refractive spherical equivalent were evaluated. ●RESULTS: 1) Average SFCT was (275. 91±55. 74)μ m in normals, that in emmetropia group, low-degree myopia, middle- degree myopia and high - degree myopia group were (290. 03± 34. 82) μ m, (287. 64 ± 51. 51) μ m, (274. 95 ± 56. 83)μ m, (248. 37 ± 67. 98) μ m; 2) the SFCT of high -degree myopia group was significant thinner than that of emmetropia group (P< 0. 05); 3) There was a significant negatives correlation between the SFCT and axial length (P<0. 01), a significant positive correlation between SFCT and myopic refractive spherical equivalent (P<0. 01). ● CONCLUSlON: the SFCT is inversely correlated with increasing axial length and myopic refractive error.