中西医结合治疗慢性胆囊炎68例临床疗效观察

摘要

目的:对中西医结合治疗慢性胆囊炎的临床疗效和安全性进行观察.方法:选取符合纳入标准的136例慢性胆囊炎患者,按照随机数字法随机分为观察组和对照组,每组68例,对照组采用常规西药治疗,观察组在对照组基础上给予柴芩利胆汤进行加减治疗,观察两组患者的临床疗效和安全性.结果:治疗后两组患者左上腹疼痛、腹胀、食欲不振、恶心、呕吐、胆囊区压痛发生率均显著降低(x2≥6.639,P均<0.05),但观察组左上腹疼痛、腹胀、食欲不振、恶心、呕吐、胆囊区压痛发生率下降更为明显(x2 =13.779、8.382、8.815、4.567、5.647,P均<0.05).两组患者治疗3个疗程后,观察组总有效率为97.0%显著性高于对照组的70.6%,差异具有统计学意义(x2 =17.568,P<0.01).两组治疗期间均未出现严重的不良反应;观察组出现皮疹6 例,发生率为8.8%,对照组出现皮疹7 例,发生率为10.3%,两组不良反应比较无显著性差异(x2 =0.085,P>0.05).结论:中西医结合治疗慢性胆囊炎含合并胆囊结石,标本兼治,其临床疗效要高于单纯西药的治疗效果.%Objective:To observe the curative effect and clinical safety of using integrative medicine for treating patients with chronic cholecystitis.Methods:136 cases of patients with chronic cholecystitis were selected and divided into an observation group and a control group (68 cases in each group) according to the random num-ber method.The control group received the conventional western medicine treatment, while the observation group was given Chaiqin Lidan decoction on the basis of the therapy in the control group.Clinical efficacy and clinical safety of two groups were recorded and compared.Results:In two groups after treatment incidences of left upper abdominal pain, abdominal distension, loss of appetite, nausea, vomiting and gallbladder area ten-derness were all significantly lower compared with those before treatment (χx2≥6.639,all P<0.05), but the incidences in the observation group were decreased more apparently (x2 =13.779, 8.382, 8.815,4.567 and 5.647, all P <0.05).After 3 courses of treatment, in the observation group the total effective rate was 97.0%,which was significantly higher than that of control group 70.6% (x2 =17.568,P<0.01).During treatment there was no severely adverse reaction in two groups;the observation group had 6 cases of erythra with the rate of 8.8%;while the control group had 7 cases of erythra with the rate of 10.3%, which had no significant difference (x2 =0.085,P>0.05) .Conclusion:Integrative medicine for treating chronic cholecysti-tis has a better curative effect, compared with only western medicine treatment.