慢性阻塞性肺疾病中医辨证分型与白细胞计数、肺功能、血气分析的相关性研究

摘要

目的：研究慢性阻塞性肺疾病（ COPD ）中医辨证分型与白细胞计数、肺功能、血气分析的相关性。方法：选取2014年1月～2015年1月收治的急性加重期COPD患者240例，根据常见的临床证型进行分型，观察COPD中医辨证分型与白细胞计数、肺功能、血气分析的相关性。结果：痰热壅肺型患者白细胞计数和中性粒细胞百分比均显著高于其他类型，差异具有统计学意义（P＜0．05）；风寒束肺型患者第一秒用力呼出量（ FEV1）、血氧分压（ PaO2）和FEV1／用力肺活量（ FVC ）显著高于其他类型，差异具有统计学意义（P＜0．05）；阳虚水停型患者二氧化碳分压（PaCO2）显著高于其他类型，差异具有统计学意义（P＜0．05）。结论：不同证型COPD患者白细胞计数、肺功能以及血气分析表现不同，可以用来作为中医辨证分析的辅助指标。%Objective: To study the correlation between syndromes of chronic obstructive pulmonary disease ( COPD) and white blood cell count, pulmonary function, blood gas analysis.Methods:240 cases with acute exacerbation of COPD were selected from our hospital from January 2014 to January 2015 based on common clinical disease types,observing the correlation between syndromes of COPD and white blood cell count, pul-monary function, blood gas analysis.Results:Leukocyte and neutrophil percentage of phlegm obstructing the pulmonary type were significantly higher than those of other types,and the difference was statistically signifi-cant (P<0.05);forced expiratory volume in the first second (FEV1), blood oxygen pressure (PaO2) and FEV1/forced vital capacity ( FVC) of cold beam Lungs were significantly higher than those of other types,and the difference was statistically significant ( P<0.05);carbon dioxide partial pressure ( PaCO2 ) of Yang defi-ciency and water stopping type was significantly higher than that of other types,and the difference was statisti-cally significant (P<0.05).Conclusion:COPD patients with different disease types have different manifesta-tions of white blood cell count, lung function and blood gas analysis,which can be used as auxiliary indexes of TCM dialectical analysis.